LR

Longevity Risk Calculator

Validated cardiovascular and chronic kidney disease calculators plus exploratory multi-disease risk curves.

1 saved
Consult-driven form

Showing 10 priority inputs for healthy longevity consult.

AgeSexSystolic blood pressureTotal cholesterolHDL-CLDL-CHbA1ceGFR+6 hidden

Activity reference: Low is under guideline targets, moderate is about guideline range, and high is above that.

Likelihood of disease by age

Heuristic, evidence-informed estimates derived from mixed sources. Risk shown assumes the current profile remains stable over time. For education only, not diagnosis or treatment decisions.

Coronary / ASCVD (proxy)
Stroke
Heart failure
Type 2 diabetes
COPD
Chronic kidney disease
Dementia
Colorectal cancer
Lung cancer
Chronic liver disease
Validated Clinical Risk Calculators
ASCVD calculator comparison

Side-by-side validated ASCVD estimates.

Clinically grounded
Kidney validated overview
Clinically grounded
KDIGO chronic kidney disease stage
G1 / A1
Low risk category from eGFR and UACR
ASCVD PCE (2013)
1.1%
Low (<5%) 10-year risk
Optimal-profile comparator: 0.8%
ASCVD Revised PCE (2018)
1.3%
Low (<5%) 10-year risk
Optimal-profile comparator: 0.9%
KFRE numeric outputs
4-variable 2-year0.0023%
4-variable 5-year0.0059%
6-variable 2-year0.0009%
6-variable 5-year0.0024%
8-variable 2-year0.0010%
8-variable 5-year0.0025%

In G1-G2, CKD diagnosis requires persistent kidney damage markers (for example albuminuria) or structural abnormalities.

PCE uses White-cohort equations for non-Black groups here; calibration may differ by ancestry/population.

PREVENT is using the full model using HbA1c and UACR; SDI is left missing because ZIP/SDI is not captured here.

ESC SCORE2 regional calibration is inferred as moderate-risk Europe here unless a mapped European country is selected; United Kingdom maps to low-risk Europe.

SCORE2-Diabetes uses current age as the diabetes-onset age surrogate here because age at diagnosis is not yet captured on this page.

KFRE is generally used for CKD populations (often eGFR <60 and/or significant albuminuria).

ASCVD Calculator Comparison

Side-by-side outputs from the currently integrated ASCVD calculators using the inputs on this page.

ASCVD PCE (2013)

US primary prevention

1.1%
10-year ASCVD risk
Inputs used
AgeSexPCE race modelTotal cholesterolHDL-CSystolic blood pressureBlood pressure medication statusSmokingDiabetes diagnosis

PCE uses White-cohort equations for non-Black groups here; calibration may differ by ancestry/population.

ASCVD Revised PCE (2018)

US primary prevention

1.3%
10-year ASCVD risk
Inputs used
AgeSexPCE race modelTotal cholesterolHDL-CSystolic blood pressureBlood pressure medication statusSmokingDiabetes diagnosis

PCE uses White-cohort equations for non-Black groups here; calibration may differ by ancestry/population.

PREVENT Total CVD 10y

AHA PREVENT primary prevention

1.4%
10-year total CVD risk (full model using HbA1c and UACR; SDI is left missing because ZIP/SDI is not captured here)
Inputs used
AgeSexTotal cholesterolHDL-CSystolic blood pressureBlood pressure medication statusSmokingBMIeGFRStatin useDiabetes diagnosis or HbA1c >=6.5%HbA1cUACR

PREVENT is using the full model using HbA1c and UACR; SDI is left missing because ZIP/SDI is not captured here.

PREVENT ASCVD 10y

AHA PREVENT primary prevention

1.0%
10-year ASCVD risk (full model using HbA1c and UACR; SDI is left missing because ZIP/SDI is not captured here)
Inputs used
AgeSexTotal cholesterolHDL-CSystolic blood pressureBlood pressure medication statusSmokingBMIeGFRStatin useDiabetes diagnosis or HbA1c >=6.5%HbA1cUACR

PREVENT is using the full model using HbA1c and UACR; SDI is left missing because ZIP/SDI is not captured here.

PREVENT HF 10y

AHA PREVENT primary prevention

0.5%
10-year heart failure risk (full model using HbA1c and UACR; SDI is left missing because ZIP/SDI is not captured here)
Inputs used
AgeSexTotal cholesterolHDL-CSystolic blood pressureBlood pressure medication statusSmokingBMIeGFRStatin useDiabetes diagnosis or HbA1c >=6.5%HbA1cUACR

PREVENT is using the full model using HbA1c and UACR; SDI is left missing because ZIP/SDI is not captured here.

PREVENT Total CVD 30y

AHA PREVENT primary prevention

10.5%
30-year total CVD risk (full model using HbA1c and UACR; SDI is left missing because ZIP/SDI is not captured here)
Inputs used
AgeSexTotal cholesterolHDL-CSystolic blood pressureBlood pressure medication statusSmokingBMIeGFRStatin useDiabetes diagnosis or HbA1c >=6.5%HbA1cUACR

PREVENT is using the full model using HbA1c and UACR; SDI is left missing because ZIP/SDI is not captured here.

PREVENT ASCVD 30y

AHA PREVENT primary prevention

6.8%
30-year ASCVD risk (full model using HbA1c and UACR; SDI is left missing because ZIP/SDI is not captured here)
Inputs used
AgeSexTotal cholesterolHDL-CSystolic blood pressureBlood pressure medication statusSmokingBMIeGFRStatin useDiabetes diagnosis or HbA1c >=6.5%HbA1cUACR

PREVENT is using the full model using HbA1c and UACR; SDI is left missing because ZIP/SDI is not captured here.

PREVENT HF 30y

AHA PREVENT primary prevention

4.4%
30-year heart failure risk (full model using HbA1c and UACR; SDI is left missing because ZIP/SDI is not captured here)
Inputs used
AgeSexTotal cholesterolHDL-CSystolic blood pressureBlood pressure medication statusSmokingBMIeGFRStatin useDiabetes diagnosis or HbA1c >=6.5%HbA1cUACR

PREVENT is using the full model using HbA1c and UACR; SDI is left missing because ZIP/SDI is not captured here.

SCORE2

ESC primary prevention (moderate region)

1.7%
10-year fatal and non-fatal CVD risk
Inputs used
AgeSexSmokingSystolic blood pressureTotal cholesterolHDL-CCountry to infer ESC region

ESC SCORE2 regional calibration is inferred as moderate-risk Europe here unless a mapped European country is selected; United Kingdom maps to low-risk Europe.

SCORE2-OP

ESC older persons (moderate region)

N/A
10-year fatal and non-fatal CVD risk
Inputs used
AgeSexSmokingSystolic blood pressureTotal cholesterolHDL-CCountry to infer ESC region

ESC SCORE2 regional calibration is inferred as moderate-risk Europe here unless a mapped European country is selected; United Kingdom maps to low-risk Europe.

SCORE2-Diabetes

ESC diabetes model (moderate region)

N/A
10-year fatal and non-fatal CVD risk in type 2 diabetes
Inputs used
AgeSexSmokingSystolic blood pressureTotal cholesterolHDL-CHbA1ceGFRCountry to infer ESC region

ESC SCORE2 regional calibration is inferred as moderate-risk Europe here unless a mapped European country is selected; United Kingdom maps to low-risk Europe.

SCORE2-Diabetes uses current age as the diabetes-onset age surrogate here because age at diagnosis is not yet captured on this page.

Exploratory 10-year risk at age 42
Heuristic
Coronary / ASCVD (proxy)

Broad heart attack/ischemic vascular proxy driven mainly by age, blood pressure, lipids, smoking, and glucose-related risk.

6.9%
Stroke

Exploratory stroke risk estimate weighted strongly by age, blood pressure, smoking, and diabetes-related risk.

1.9%
Heart failure

Risk of developing heart failure, influenced by age, blood pressure, BMI, glucose status, and kidney function.

1.6%
Type 2 diabetes

Estimated type 2 diabetes risk driven most by HbA1c, BMI, family history, and physical activity.

5.6%
COPD

Exploratory chronic lung disease risk estimate where smoking status is the dominant driver, with age also contributing.

2.2%
Chronic kidney disease

Estimated chronic kidney disease risk proxy weighted by kidney function (eGFR), blood pressure, and glucose-related risk.

2.5%
Dementia

Age-weighted dementia risk proxy adjusted by activity level, smoking, blood pressure, and metabolic factors.

0.7%
Colorectal cancer

Exploratory colorectal cancer risk estimate weighted by age, family history, activity, BMI, and alcohol use.

1.2%
Lung cancer

Exploratory lung cancer risk estimate dominated by smoking status and age, with smaller family history effects.

0.4%
Chronic liver disease

Exploratory chronic liver disease risk estimate weighted by alcohol use, metabolic markers, BMI, and age.

1.0%